In vivo enhancer analysis of human conserved non-coding sequences

L Pennacchio, Nadav Ahituv, Alan M Moses, +16

Nature

Transcriptional RegulationGeneticsVivo Enhancer AnalysisGene CharacterizationGene Expression +2

The right ventricle, outflow tract, and ventricular septum comprise a restricted expression domain within the secondary/anterior heart field

Michael P. Verzi, David J. McCulley, Sarah De Val, +2

Developmental Biology

Heart FailureCardiac MechanicPhysiologyExpression DomainOutflow Tract +5

Foxn4 directly regulates <i>tbx2b</i> expression and atrioventricular canal formation

C. Neil, Robin M. Shaw, Sarah De Val, +4

Genes & Development

Cardiac MuscleGeneticsGene Regulatory NetworkCellular PhysiologyTranscriptional Regulation +17

Combinatorial Regulation of Endothelial Gene Expression by Ets and Forkhead Transcription Factors

Sarah De Val, C. Neil, Stryder M. Meadows, +12

Cell

Systems BiologyAngiogenesisForkhead Transcription FactorsMedicineNatural Sciences +10

AdPLA ablation increases lipolysis and prevents obesity induced by high-fat feeding or leptin deficiency

Kathy Jaworski, Maryam Ahmadian, Robin E. Duncan, +10

Nature Medicine

ObesityNutritionMetabolic SyndromeHigh-fat FeedingEnergy Homeostasis +9

<i>Gata4</i>expression in lateral mesoderm is downstream of BMP4 and is activated directly by Forkhead and GATA transcription factors through a distal enhancer element

Anabel Rojas, Sarah De Val, Analeah B. Heidt, +3

Development

Lateral MesodermTranscriptional RegulationBmp4-null EmbryosDevelopmental BiologyTissue Development +13

Analysis of <i>Dll4</i> regulation reveals a combinatorial role for Sox and Notch in arterial development

Natalia Sacilotto, Rui Monteiro, Martin Fritzsche, +10

Proceedings of the National Academy of Sciences

A Polymorphic p53 Response Element in KIT Ligand Influences Cancer Risk and Has Undergone Natural Selection

Jorge Zerón-Medina, Xuting Wang, Emmanouela Repapi, +14

Cell

Tumor HeterogeneityMedicineGeneticsCancer GenomicsCancer Biology +8

Maintenance of blastemal proliferation by functionally diverse epidermis in regenerating zebrafish fins

Yoonsung Lee, Danyal Hami, Sarah De Val, +5

Developmental Biology

Regenerative MedicineDevelopmental BiologyTissue DevelopmentInjury BiologyZebrafish Fins +9

MEF2 transcription factors are key regulators of sprouting angiogenesis

Natalia Sacilotto, Kira M. Chouliaras, Leonid L. Nikitenko, +18

Genes & Development

Endothelial CellsTumor BiologyTranscriptional RegulationAngiogenesisSignaling Pathway +14