Human airway epithelial cells produce IP-10 (CXCL10) in vitro and in vivo upon rhinovirus infection

Jason Spurrell, Shahina Wiehler, Raza S. Zaheer, +2

American Journal of Physiology-Lung Cellular and Molecular Physiology

Rhinovirus InfectionType 1Inflammatory Lung DiseaseLung InflammationViral Pathogenesis +12

Human rhinovirus infection enhances airway epithelial cell production of growth factors involved in airway remodeling

Richard Leigh, Wale Oyelusi, Shahina Wiehler, +4

Journal of Allergy and Clinical Immunology

Viral ReplicationLung InflammationRespiratory DiseasesHuman Rhinovirus InfectionPathogenesis +8

Human Rhinovirus–Induced Epithelial Production of CXCL10 Is Dependent upon IFN Regulatory Factor-1

Raza S. Zaheer, David Proud

American Journal of Respiratory Cell and Molecular Biology

Cigarette Smoke Modulates Expression of Human Rhinovirus-Induced Airway Epithelial Host Defense Genes

David Proud, Magdalena H. Hudy, Shahina Wiehler, +9

PLoS ONE

AsthmaTobacco ControlCse-induced Gene ExpressionAllergyLung Inflammation +12

Nitric oxide inhibits human rhinovirus-induced transcriptional activation of CXCL10 in airway epithelial cells

Rommy Koetzler, Raza S. Zaheer, Shahina Wiehler, +3

Journal of Allergy and Clinical Immunology

InflammationViral PathogenesisImmunologyAntiviral ResponseVirology +3

Selective Transcriptional Down-Regulation of Human Rhinovirus-Induced Production of CXCL10 from Airway Epithelial Cells via the MEK1 Pathway

Raza S. Zaheer, Rommy Koetzler, Neil S. Holden, +2

The Journal of Immunology

Mechanisms of human complement factor B induction in sepsis and inhibition by activated protein C

Kim Goring, Yong Huang, Connie Mowat, +7

American Journal of Physiology-Cell Physiology

Innate Immune SystemImmunologyImmune RegulationPathologyImmunologic Mechanism +15

The serine protease-mediated increase in intestinal epithelial barrier function is dependent on occludin and requires an intact tight junction

Natalie J. Ronaghan, Judie Shang, Vadim Iablokov, +7

American Journal of Physiology-Gastrointestinal and Liver Physiology

Protein SecretionCell AdhesionImmunologyGastroenterologyPathology +17

Nitric oxide inhibits IFN regulatory factor 1 and nuclear factor-κB pathways in rhinovirus-infected epithelial cells

Rommy Koetzler, Raza S. Zaheer, Robert Newton, +1

Journal of Allergy and Clinical Immunology

InflammationCell SignalingInnate Immune SystemViral PathogenesisImmunology +10

Human rhinovirus-induced ISG15 selectively modulates epithelial antiviral immunity

Raza S. Zaheer, Shahina Wiehler, M. H. Hudy, +4

Mucosal Immunology