Mark E. Fitzgerald

<i>MTAP</i> deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells

Gregory V. Kryukov, Frederick H. Wilson, Jason R. Ruth et al. · Science · 2016 · 653 citations

Medicine, Cancer Biology, Oncology +17

Structural Characterization of Degrader-Induced Ternary Complexes Using Hydrogen–Deuterium Exchange Mass Spectrometry and Computational Modeling: Implications for Structure-Based Design

Scott J. Eron, Hongwei Huang, Roman V. Agafonov et al. · ACS Chemical Biology · 2021 · 61 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Diversity-Oriented Synthesis Yields a Novel Lead for the Treatment of Malaria

Richard W. Heidebrecht, Carol A. Mulrooney, Christopher P. Austin et al. · ACS Medicinal Chemistry Letters · 2011 · 53 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Diversity-Oriented Synthesis-Facilitated Medicinal Chemistry: Toward the Development of Novel Antimalarial Agents

Eamon Comer, Jennifer A. Beaudoin, Nobutaka Kato et al. · Journal of Medicinal Chemistry · 2014 · 39 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Build/Couple/Pair Strategy for the Synthesis of Stereochemically Diverse Macrolactams via Head-to-Tail Cyclization

Mark E. Fitzgerald, Carol A. Mulrooney, Jeremy R. Duvall et al. · ACS Combinatorial Science · 2012 · 39 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +17