Ka Diam Go

Thermal proximity coaggregation for system-wide profiling of protein complex dynamics in cells

Chris Soon Heng Tan, Ka Diam Go, Xavier Bisteau et al. · Science · 2018 · 224 citations · Full text

Protein Assembly, Molecular Biology, Protein Folding +21

Cellular thermal shift assay for the identification of drug–target interactions in the Plasmodium falciparum proteome

Jerzy M. Dziekan, Grennady Wirjanata, Lingyun Dai et al. · Nature Protocols · 2020 · 134 citations

Proteomic Technology, Drug–target Interactions, Drug Target +11

Dual blockade of the lipid kinase PIP4Ks and mitotic pathways leads to cancer-selective lethality

Mayumi Kitagawa, Pei-Ju Liao, Kyung Hee Lee et al. · Nature Communications · 2017 · 77 citations · Full text

Pip4k Lipid Kinases, Cancer Biology, Tumor Biology +17

An efficient proteome-wide strategy for discovery and characterization of cellular nucleotide-protein interactions

Yan Ting Lim, Nayana Prabhu, Lingyun Dai et al. · PLoS ONE · 2018 · 52 citations · Full text

Thymidine Metabolites, Efficient Proteome-wide Strategy, Metabolomic Profiling +21

Identification of an inhibitory pocket in falcilysin provides a new avenue for malaria drug development

Grennady Wirjanata, Jianqing Lin, Jerzy M. Dziekan et al. · Cell chemical biology · 2024 · 19 citations

Pharmaceutical Science, Inhibitory Pocket, Biochemistry +9