SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration

Matthew D. Figley, Weixi Gu, Jeffrey D. Nanson, +21

Neuron

Nmn/nad+ RatioMolecular NeuroscienceSignal TransductionMitochondrial FunctionMolecular Biology +9

PTENα, a PTEN Isoform Translated through Alternative Initiation, Regulates Mitochondrial Function and Energy Metabolism

Hui Liang, Shiming He, Jingyi Yang, +8

Cell Metabolism

Signal TransductionMitochondrial FunctionBiochemistryPten Isoform TranslatedRegulates Mitochondrial Function +10

Genetic Characterization of the Chlorothricin Gene Cluster as a Model for Spirotetronate Antibiotic Biosynthesis

Xinying Jia, Zhenhua Tian, Lei Shao, +5

Chemistry & Biology

Spirotetronate Antibiotic BiosynthesisBiosynthesisAntimicrobial Resistance GeneBiochemistryMicrobial Genetics +10

Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities

Mintu Chandra, Yanni K.‐Y. Chin, Caroline Mas, +13

Nature Communications

Phox HomologyProteinlipid InteractionMolecular BiologyLipid MovementHuman Phox Homology +18

An enzymatic [4+2] cyclization cascade creates the pentacyclic core of pyrroindomycins

Zhenhua Tian, Peng Sun, Yan Yan, +10

Nature Chemical Biology

Medicinal ChemistryBiosynthesisBioorganic ChemistryEngineeringBiochemistry +7

DOTA-Amide Lanthanide Tag for Reliable Generation of Pseudocontact Shifts in Protein NMR Spectra

Bim Graham, Choy Theng Loh, James Swarbrick, +9

Bioconjugate Chemistry

Protein AssemblyBiomolecular Structure PredictionMagnetic ResonanceMolecular BiologyReliable Generation +15

Transcriptome and venom proteome of the box jellyfish Chironex fleckeri

Diane L. Brinkman, Xinying Jia, Jeremy Potriquet, +4

BMC Genomics

GSK-3β–Regulated N-Acetyltransferase 10 Is Involved in Colorectal Cancer Invasion

Hong Zhang, Wei Hou, Huali Wang, +8

Clinical Cancer Research

Semienzymatic Cyclization of Disulfide-rich Peptides Using Sortase A

Xinying Jia, Soohyun Kwon, Ching-I Anderson Wang, +7

Journal of Biological Chemistry

Designing antimicrobial peptides using deep learning and molecular dynamic simulations

Qiushi Cao, Cheng Ge, Xuejie Wang, +13

Briefings in Bioinformatics