Jeffrey D. Nanson

NAD ⁺ cleavage activity by animal and plant TIR domains in cell death pathways

S. Horsefield, Hayden Burdett, Xiaoxiao Zhang et al. · Science · 2019 · 498 citations · Full text

SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration

Matthew D. Figley, Weixi Gu, Jeffrey D. Nanson et al. · Neuron · 2021 · 326 citations · Full text

Nmn/nad+ Ratio, Molecular Neuroscience, Signal Transduction +11

Cyclic ADP ribose isomers: Production, chemical structures, and immune signaling

M.K. Manik, Yun Shi, Sulin Li et al. · Science · 2022 · 141 citations · Full text

Structural basis of SARM1 activation, substrate recognition, and inhibition by small molecules

Yun Shi, Philip S. Kerry, Jeffrey D. Nanson et al. · Molecular Cell · 2022 · 130 citations · Full text

MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography

Max T. B. Clabbers, Susannah Holmes, Timothy W. Muusse et al. · Nature Communications · 2021 · 95 citations · Full text