Andrew R. Frazer

Engineered enzymes that retain and regenerate their cofactors enable continuous-flow biocatalysis

Carol J. Hartley, Charlotte C. Williams, Judith A. Scoble et al. · Nature Catalysis · 2019 · 134 citations

Continuous-flow Biocatalysis, Engineering, Enzymes +10

Galactose Oxidase Variants for the Oxidation of Amino Alcohols in Enzyme Cascade Synthesis

Susanne Herter, Shane McKenna, Andrew R. Frazer et al. · ChemCatChem · 2015 · 56 citations

Biosynthesis, Bioorganic Chemistry, Engineering +15

Altered cofactor binding affects stability and activity of human UDP-galactose 4′-epimerase: Implications for type III galactosemia

Thomas J. McCorvie, Ying Liu, Andrew R. Frazer et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2012 · 34 citations · Full text

Cellular Enzymology, Biochemistry, Type Iii Galactosemia +10

Sugar analog synthesis by in vitro biocatalytic cascade: A comparison of alternative enzyme complements for dihydroxyacetone phosphate production as a precursor to rare chiral sugar synthesis

Carol J. Hartley, Nigel G. French, Judith A. Scoble et al. · PLoS ONE · 2017 · 20 citations · Full text

Engineering, Aldo-keto Reductase, Batch Biocatalysis +18

A Bacterial Enrichment Study and Overview of the Extractable Lipids from Paleosols in the Dry Valleys, Antarctica: Implications for Future Mars Reconnaissance

Kris M. Hart, Michal Szpak, William C. Mahaney et al. · Astrobiology · 2011 · 18 citations