CaMKII is a RIP3 substrate mediating ischemia- and oxidative stress–induced myocardial necroptosis

Ting Zhang, Yan Zhang, Mingyao Cui, +14

Nature Medicine

InflammationCardiac MuscleCardiovascular DiseaseBiochemistryMedicine +10

AMP Activated Protein Kinase-α2 Deficiency Exacerbates Pressure-Overload–Induced Left Ventricular Hypertrophy and Dysfunction in Mice

Ping Zhang, Xinli Hu, Xin Xu, +8

Hypertension

Cardiac MuscleCardiomyopathyHeart FailureMolecular PhysiologyDevelopmental Biology +12

Betulinic acid inhibits pyroptosis in spinal cord injury by augmenting autophagy via the AMPK-mTOR-TFEB signaling pathway

Chen‐Yu Wu, Huanwen Chen, Rong Zhuang, +9

International Journal of Biological Sciences

Negative regulation of AMPK signaling by high glucose via E3 ubiquitin ligase MG53

Peng Jiang, Lejiao Ren, Zhi Li, +13

Molecular Cell

Signal TransductionMolecular PhysiologyHigh GlucoseSignaling PathwayPhysiology +8

Inducible Nitric Oxide Synthase Deficiency Protects the Heart From Systolic Overload–Induced Ventricular Hypertrophy and Congestive Heart Failure

Ping Zhang, Xin Xu, Xinli Hu, +3

Circulation Research

Heart FailureCardiovascular FunctionOxidative StressInos MonomerCongestive Heart Failure +14

Upregulation of MG53 Induces Diabetic Cardiomyopathy Through Transcriptional Activation of Peroxisome Proliferation-Activated Receptor α

Fenghua Liu, Ruisheng Song, Yuanqing Feng, +11

Circulation

Receptor-interacting Protein 140 Directly Recruits Histone Deacetylases for Gene Silencing

Li‐Na Wei, Xinli Hu, Dhyan Chandra, +2

Journal of Biological Chemistry

Dimethylarginine Dimethylaminohydrolase-1 Is the Critical Enzyme for Degrading the Cardiovascular Risk Factor Asymmetrical Dimethylarginine

Xinli Hu, Dorothee Atzler, Xin Xu, +8

Arteriosclerosis Thrombosis and Vascular Biology

Glucose-Sensitive Myokine/Cardiokine MG53 Regulates Systemic Insulin Response and Metabolic Homeostasis

Hongkun Wu, Yan Zhang, Chunmei Cao, +19

Circulation

Extracellular Superoxide Dismutase Deficiency Exacerbates Pressure Overload–Induced Left Ventricular Hypertrophy and Dysfunction

Zhongbing Lu, Xin Xu, Xinli Hu, +8

Hypertension

Extracellular Superoxide DismutaseHeart FailureGlutathione DisulfideLipid PeroxidationCardiovascular Function +14