Takamitsu Komiyama

Histone deacetylase inhibitor suppression of autoantibody‐mediated arthritis in mice via regulation of p16^INK4a and p21^WAF1/Cip1 expression

Keiichiro Nishida, Takamitsu Komiyama, Shin‐Ichi Miyazawa et al. · Arthritis & Rheumatism · 2004 · 214 citations

Trichostatin A, a histone deacetylase inhibitor, suppresses synovial inflammation and subsequent cartilage destruction in a collagen antibody-induced arthritis mouse model

Y. Nasu, Keiichiro Nishida, Shinichi Miyazawa et al. · Osteoarthritis and Cartilage · 2008 · 146 citations · Full text

Histone Deacetylase Inhibitor, Immunology, Dermatology +17

Intra-articular injection of interleukin-4 decreases nitric oxide production by chondrocytes and ameliorates subsequent destruction of cartilage in instability-induced osteoarthritis in rat knee joints

Masanori Yorimitsu, Keiichiro Nishida, Akira Shimizu et al. · Osteoarthritis and Cartilage · 2008 · 60 citations · Full text

Inflammation, Rheumatology, Rheumatoid Disorder +12

Inhibition of histone deacetylase down-regulates the expression of hypoxia-induced vascular endothelial growth factor by rheumatoid synovial fibroblasts

Hiroaki Manabe, Y. Nasu, Takamitsu Komiyama et al. · Inflammation Research · 2008 · 52 citations

Inflammation, Histone Deacetylase, Rheumatoid Synovial Fibroblasts +11

Interleukin-4 downregulates the cyclic tensile stress-induced matrix metalloproteinases-13 and cathepsin B expression by rat normal chondrocytes.

Hideyuki Doi, Keiichiro Nishida, Masanori Yorimitsu et al. · PubMed · 2008 · 40 citations

Immunology, Pathology, Musculoskeletal Research +18