Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation

Torkild Visnes, Armando Cázares‐Körner, Wenjing Hao, +37

Science

Oxidized Guanine Base Lesions Function in 8-Oxoguanine DNA Glycosylase-1-mediated Epigenetic Regulation of Nuclear Factor κB-driven Gene Expression

Lang Pan, Bing Zhu, Wenjing Hao, +9

Journal of Biological Chemistry

ChromatinTranscriptional RegulationChromatin StructureChromatin RemodelingMolecular Regulation +10

8-Oxoguanine DNA Glycosylase-1 Augments Proinflammatory Gene Expression by Facilitating the Recruitment of Site-Specific Transcription Factors

Xueqing Ba, Attila Bácsi, Jixian Luo, +5

The Journal of Immunology

Trypanosoma cruzi Induces the Reactive Oxygen Species-PARP-1-RelA Pathway for Up-regulation of Cytokine Expression in Cardiomyocytes

Xueqing Ba, Shivali Gupta, Mercy M. Davidson, +1

Journal of Biological Chemistry

MitophagyImmunologyCell DeathPathologyReactive Oxygen Species +14

Innate Inflammation Induced by the 8-Oxoguanine DNA Glycosylase-1–KRAS–NF-κB Pathway

Leopoldo Aguilera-Aguirre, Attila Bácsi, Zsolt Radák, +6

The Journal of Immunology

OGG1-initiated base excision repair exacerbates oxidative stress-induced parthanatos

Ruoxi Wang, Chunshuang Li, Ping Qiao, +7

Cell Death and Disease

BRG1 promotes DNA double-strand break repair by facilitating the replacement of RPA with RAD51

Wenjing Qi, Ruoxi Wang, Hongyu Chen, +6

Journal of Cell Science

Recruited monocytic myeloid-derived suppressor cells promote the arrest of tumor cells in the premetastatic niche through an IL-1β-mediated increase in E-selectin expression

Huifang Shi, Juechao Zhang, Xiaoqing Han, +6

International Journal of Cancer

Inflammatory Lung DiseaseLung InflammationImmunologyImmune RegulationImmunoediting +23

Down-regulation of 8-oxoguanine DNA glycosylase 1 expression in the airway epithelium ameliorates allergic lung inflammation

Attila Bácsi, Leopoldo Aguilera-Aguirre, Bartosz Szczęsny, +5

DNA repair

InflammationAsthmaAllergyInflammatory Lung DiseaseLung Inflammation +10

8-Oxoguanine DNA glycosylase-1 links DNA repair to cellular signaling via the activation of the small GTPase Rac1

György Hajas, Attila Bácsi, Leopoldo Aguilera-Aguirre, +6

Free Radical Biology and Medicine

ChromatinGenome InstabilityChromatin RemodelingNatural SciencesMolecular Biology +5