Concepedia

Ryan Casement

RC

6

Publications

420

Citations

6

H-Index

2021

Active since

Affiliations

University of Dundee(Current)

CeMM Research Center for Molecular Medicine

Austrian Academy of Sciences

Medical Research Council

Eisai (Japan)

Ryan Casement is an author at University of Dundee specializing in molecular biology, protein assembly, and natural sciences.

Top concepts

Molecular BiologyProtein FoldingNatural SciencesProtein AssemblyMedicineBiochemistryCrystallographySmall MoleculesProtein DegradationProtein Engineering

Publications per year

2021–2024

6

Publications

6

Targeted protein degradation via intramolecular bivalent glues

Oliver Hsia, Matthias Hinterndorfer, Angus D. Cowan et al. · Nature · 2024 · 155 citations · Full text

Functional E3 ligase hotspots and resistance mechanisms to small-molecule degraders

Alexander Hanzl, Ryan Casement, Hana Imrichová et al. · Nature Chemical Biology · 2022 · 103 citations · Full text

Protein Assembly, Biochemistry, Protein Folding +7

Mechanistic and Structural Features of PROTAC Ternary Complexes

Ryan Casement, Adam G. Bond, Conner Craigon et al. · Methods in molecular biology · 2021 · 88 citations · Full text

Structural Features, Coordination Complex, Molecular Biology +3

Structure-based design of a phosphotyrosine-masked covalent ligand targeting the E3 ligase SOCS2

Sarath Ramachandran, Nikolai Makukhin, Kevin Haubrich et al. · Nature Communications · 2023 · 35 citations · Full text

Targeted protein degradation via intramolecular bivalent glues

Oliver Hsia, Matthias Hinterndorfer, Angus D. Cowan et al. · 2023 · 25 citations · Full text

Protein Chemistry, Protein Quality Control, Protein Function +15

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