Inhibitions of acid secretion by E3810 and omeprazole, and their reversal by glutathione

Hideaki Fujisaki, Kiyoshi Oketani, Manabu Murakami, +6

Biochemical Pharmacology

BiochemistryMedicinePhysiologyAcid SecretionMechanism Of Action +4

Antiulcer effect of geranylgeranylacetone, a new acyclic polyisoprenoid on experimentally induced gastric and duodenal ulcers in rats.

Manabu Murakami, Kiyoshi Oketani, Hideaki Fujisaki, +2

PubMed

Molecular PharmacologyMedicinal ChemistryAnti-inflammatoryAnti-inflammatory AgentsNew Acyclic Polyisoprenoid +12

Effects of the antiulcer drug geranylgeranylacetone on aspirin-induced gastric ulcers in rats.

Manabu Murakami, Kiyoshi Oketani, Hideaki Fujisaki, +3

The Japanese Journal of Pharmacology

Novel Dual Inhibitors of 5-Lipoxygenase and Thromboxane A2 Synthetase: Synthesis and Structure-Activity Relationships of 3-Pyridylmethyl-Substituted 2-Amino-6-hydroxybenzothiazole Derivatives

Shigeki Hibi, Yasushi Okamoto, Katsuya Tagami, +6

Journal of Medicinal Chemistry

Effect of geranylgeranylacetone on aspirin-induced changes in gastric glycoproteins.

Kiyoshi Oketani, Manabu Murakami, Hideaki Fujisaki, +2

The Japanese Journal of Pharmacology

Molecular PharmacologyAllergyBiochemistryGastric GlycoproteinsGastrointestinal Pharmacology +11

Effect of E3040, an inhibitor of 5-lipoxygenase and thromboxane synthase, on rat bowel damage induced by lipopolysaccharide

Kiyoshi Oketani, Takashi Inoue, Manabu Murakami

European Journal of Pharmacology

InflammationAnti-inflammatoryBiochemistryMedicineLipid Peroxidation +5

In vitro effects of E3040, a dual inhibitor of 5-lipoxygenase and thromboxane A2 synthetase, on eicosanoid production

Kiyoshi Oketani, N. Nagakura, K Harada, +1

European Journal of Pharmacology

Dual InhibitorThromboxane A2 SynthetaseBiosynthesisOxysterolBiochemistry +5

Effects of the Proton Pump Inhibitor, E3810, on Gastric Secretion and Gastric and Duodenal Ulcers or Erosions in Rats

Hideaki Fujisaki, Kiyoshi Oketani, Manabu Murakami, +4

Clinical Drug Investigation

Gastric SecretionMedicinePhysiologyGastroenterologyDuodenal Ulcers +5

Phase 1 study on the safety and efficacy of E6011, antifractalkine antibody, in patients with Crohn's disease

Katsuyoshi Matsuoka, Makoto Naganuma, Toshifumi Hibi∥, +8

Journal of Gastroenterology and Hepatology

Effect of geranylgeranylacetone (GGA) on gastric lesions induced by topical aspirin plus HCl.

Manabu Murakami, Kiyoshi Oketani, Hideaki Fujisaki, +1

The Japanese Journal of Pharmacology

Topical AspirinGastrointestinal PharmacologyMedicineGastric LesionsGastroenterology +3