María‐Jesús Pérez‐Pérez

Blocking Blood Flow to Solid Tumors by Destabilizing Tubulin: An Approach to Targeting Tumor Growth

María‐Jesús Pérez‐Pérez, Eva‐María Priego, Oskía Bueno et al. · Journal of Medicinal Chemistry · 2016 · 181 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'',2''- oxathiole-2'',2'-dioxide)pyrimidine (TSAO) nucleoside analogues: highlyselective inhibitors of human immunodeficiency virus type 1 that are targeted at the viral reverse transcriptase.

Jan Balzarini, María‐Jesús Pérez‐Pérez, Ana San‐Félix et al. · Proceedings of the National Academy of Sciences · 1992 · 162 citations

Medicine, Medicinal Chemistry, Pharmacology +17

HIV-1-Specific Reverse Transcriptase Inhibitors Show Differential Activity against HIV-1 Mutant Strains Containing Different Amino Acid Substitutions in the Reverse Transcriptase

Jan Balzarini, Anna Karlsson, María‐Jesús Pérez‐Pérez et al. · Virology · 1993 · 153 citations

Life Sciences, Biochemistry, Molecular Biology +12

3'-Spiro nucleosides, a new class of specific human immunodeficiency virus type 1 inhibitors: synthesis and antiviral activity of [2', 5'-bis-O-(tert-butyldimethylsilyl)-.beta.-D-xylo- and -ribofuranose]-3'-spiro-5''-[4''-amino-1'', 2''-oxathiole 2'', 2''-dioxide] (TSAO) pyrimidine nucleosides

María‐José Camarasa, María‐Jesús Pérez‐Pérez, Ana San‐Félix et al. · Journal of Medicinal Chemistry · 1992 · 129 citations

Pharmacy, Medicinal Chemistry, Drug Discovery +9

Kinetics of inhibition of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase by the novel HIV-1-specific nucleoside analogue [2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]-3'-spiro-5 “- (4”-amino-1“,2”-oxathiole-2“,2”-dioxide)thymine (TSAO-T).

Jan Balzarini, María‐Jesús Pérez‐Pérez, Ana San‐Félix et al. · Journal of Biological Chemistry · 1992 · 119 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13