Kenneth Weichert

Crystal structure of the human PRMT5:MEP50 complex

Stephen Antonysamy, Zahid Bonday, Robert M. Campbell et al. · Proceedings of the National Academy of Sciences · 2012 · 363 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Aurora A Kinase Inhibition Is Synthetic Lethal with Loss of the <i>RB1</i> Tumor Suppressor Gene

Xueqian Gong, Jian Du, Stephen H. Parsons et al. · Cancer Discovery · 2018 · 233 citations

Life Sciences, Oncology, Pharmacology +17

LLY-283, a Potent and Selective Inhibitor of Arginine Methyltransferase 5, PRMT5, with Antitumor Activity

Zahid Bonday, Guillermo S. Cortez, Michael J. Grogan et al. · ACS Medicinal Chemistry Letters · 2018 · 181 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +8

EC144 Is a Potent Inhibitor of the Heat Shock Protein 90

Jiandong Shi, Ryan W. Van De Water, Kevin Hong et al. · Journal of Medicinal Chemistry · 2012 · 72 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +10

Computational stabilization of T cell receptors allows pairing with antibodies to form bispecifics

Karen Froning, Jack B. Maguire, Arlene Sereno et al. · Nature Communications · 2020 · 38 citations · Full text

Life Sciences, Immunology, Molecular Biology +17