Arlene Sereno

Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface

Steven M. Lewis, Xiufeng Wu, Anna Pustilnik et al. · Nature Biotechnology · 2014 · 241 citations

Pharmacy, Biotechnology, Immunology +16

A stable IgG-like bispecific antibody targeting the epidermal growth factor receptor and the type I insulin-like growth factor receptor demonstrates superior anti-tumor activity

Jianying Dong, Arlene Sereno, Dikran Aivazian et al. · mAbs · 2011 · 79 citations · Full text

Pharmacy, Oncology, Pharmacology +17

Combination of Two Insulin-Like Growth Factor-I Receptor Inhibitory Antibodies Targeting Distinct Epitopes Leads to an Enhanced Antitumor Response

Jianying Dong, Stephen J. Demarest, Arlene Sereno et al. · Molecular Cancer Therapeutics · 2010 · 68 citations

Medicine, Medicinal Chemistry, Oncology +17

Fab-based bispecific antibody formats with robust biophysical properties and biological activity

Xiufeng Wu, Arlene Sereno, Flora Huang et al. · mAbs · 2015 · 65 citations · Full text

Pharmacy, Biochemistry, Biotechnology +17

Stable IgG-like Bispecific Antibodies Directed toward the Type I Insulin-like Growth Factor Receptor Demonstrate Enhanced Ligand Blockade and Anti-tumor Activity

Jianying Dong, Arlene Sereno, William B. Snyder et al. · Journal of Biological Chemistry · 2010 · 38 citations · Full text

Medicine, Cancer Biology, Oncology +14