Karen Froning

CD8+ T cells in psoriatic lesions preferentially use T-cell receptor V beta 3 and/or V beta 13.1 genes.

Jennie C.C. Chang, Larry Smith, Karen Froning et al. · Proceedings of the National Academy of Sciences · 1994 · 233 citations · Full text

V Beta, Immunology, Immune Regulation +20

Aurora A Kinase Inhibition Is Synthetic Lethal with Loss of the <i>RB1</i> Tumor Suppressor Gene

Xueqian Gong, Jian Du, Stephen H. Parsons et al. · Cancer Discovery · 2018 · 220 citations

A Novel Mode of Gleevec Binding Is Revealed by the Structure of Spleen Tyrosine Kinase

S. Atwell, J.M. Adams, John Badger et al. · Journal of Biological Chemistry · 2004 · 190 citations · Full text

SGX523 is an exquisitely selective, ATP-competitive inhibitor of the MET receptor tyrosine kinase with antitumor activity <i>in vivo</i>

Sean G. Buchanan, J. Hendle, Patrick S. Lee et al. · Molecular Cancer Therapeutics · 2009 · 130 citations

Gene Amplification, Antitumor Activity, Chemoprevention Strategy +17

Computationally Designed Bispecific Antibodies using Negative State Repertoires

Andrew Leaver‐Fay, Karen Froning, S. Atwell et al. · Structure · 2016 · 62 citations · Full text

Systems Biology, Negative State Repertoires, Natural Sciences +7