T.B. Shaik

Structure-Based Design and Synthesis of Novel Inhibitors Targeting HDAC8 from <i>Schistosoma mansoni</i> for the Treatment of Schistosomiasis

Tino Heimburg, Alokta Chakrabarti, Julien Lancelot et al. · Journal of Medicinal Chemistry · 2016 · 123 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants

Martin Marek, T.B. Shaik, Tino Heimburg et al. · Journal of Medicinal Chemistry · 2018 · 118 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors

Katharina Vögerl, Nghia Ong, Johanna Senger et al. · Journal of Medicinal Chemistry · 2019 · 101 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Structure-Based Design and Biological Characterization of Selective Histone Deacetylase 8 (HDAC8) Inhibitors with Anti-Neuroblastoma Activity

Tino Heimburg, Fiona R. Kolbinger, Patrik Zeyen et al. · Journal of Medicinal Chemistry · 2017 · 93 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Novel spiroindoline HDAC inhibitors: Synthesis, molecular modelling and biological studies

Margherita Brindisi, Johanna Senger, Caterina Cavella et al. · European Journal of Medicinal Chemistry · 2018 · 50 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13