Microtubule Acetylation Promotes Kinesin-1 Binding and Transport

Nathan Reed, Dawen Cai, T. Lynne Blasius, +4

Current Biology

Signal TransductionCell MotilityCytoskeletonProtein TransportIntracellular Trafficking +3

Epigenetic inheritance uncoupled from sequence-specific recruitment

Kaushik Ragunathan, Gloria Jih, Danesh Moazed

Science

Fascin, a Novel Target of β-Catenin-TCF Signaling, Is Expressed at the Invasive Front of Human Colon Cancer

Danijela Matic Vignjevic, Marie Schoumacher, Nancy Gavert, +6

Cancer Research

Two binding partners cooperate to activate the molecular motor Kinesin-1

T. Lynne Blasius, Dawen Cai, Gloria Jih, +2

The Journal of Cell Biology

Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia

Szymon Kłossowski, Hongzhi Miao, Katarzyna Kempińska, +32

Journal of Clinical Investigation

Npm1-mutated ModelsHematological MalignancySystems BiologyMixed LineageMixed-phenotype Acute Leukemia +11

Mammalian Kinesin-3 Motors Are Dimeric In Vivo and Move by Processive Motility upon Release of Autoinhibition

Jennetta W. Hammond, Dawen Cai, T. Lynne Blasius, +5

PLoS Biology

EngineeringSynaptic TransmissionMotor ControlCytoskeletonMechanotransduction +18

Recruitment dynamics of ESCRT-III and Vps4 to endosomes and implications for reverse membrane budding

Manuel Alonso Y Adell, Simona M. Migliano, Srigokul Upadhyayula, +13

eLife

Molecular BiologyRecruitment DynamicsEscrt MachineryMembrane TransportEscrt-iii Subunits +14

Unique roles for histone H3K9me states in RNAi and heritable silencing of transcription

Gloria Jih, Nahid Iglesias, Mark A. Currie, +5

Nature

<i>MIR142</i> Loss-of-Function Mutations Derepress ASH1L to Increase <i>HOXA</i> Gene Expression and Promote Leukemogenesis

Maria Trissal, Terrence N. Wong, Juo-Chin Yao, +12

Cancer Research

Automethylation-induced conformational switch in Clr4 (Suv39h) maintains epigenetic stability

Nahid Iglesias, Mark A. Currie, Gloria Jih, +5

Nature

Automethylation-induced Conformational SwitchChromatinNatural SciencesMedicineEpigenetic Change +5