Concepedia

Lorena Saelices

LS

22

Publications

877

Citations

17

H-Index

2007

Active since

Affiliations

Howard Hughes Medical Institute(Current)

The University of Texas Southwestern Medical Center

Universidad de Sevilla

Indiana University – Purdue University Indianapolis

Indiana University School of Medicine

Lorena Saelices is an author at Howard Hughes Medical Institute specializing in medicine, biochemistry, and molecular biology.

Top concepts

MedicineBiochemistryNatural SciencesMolecular BiologyProtein EngineeringBiosynthesisPharmacologyProtein SynthesisEngineeringMicrobiology

Publications per year

2007–2024

22

Publications

22

Uncovering the Mechanism of Aggregation of Human Transthyretin

Lorena Saelices, Lisa M. Johnson, Wilson Y. Liang et al. · Journal of Biological Chemistry · 2015 · 155 citations · Full text

Molecular Physiology, Biochemistry, Medicine +6

Amyloid seeding of transthyretin by ex vivo cardiac fibrils and its inhibition

Lorena Saelices, Kevin Chung, Ji Hun Lee et al. · Proceedings of the National Academy of Sciences · 2018 · 93 citations · Full text

Cardiac Muscle, Heart Failure, Engineering +17

Cryo-EM structures of hIAPP fibrils seeded by patient-extracted fibrils reveal new polymorphs and conserved fibril cores

Qin Cao, David R. Boyer, M.R. Sawaya et al. · Nature Structural & Molecular Biology · 2021 · 81 citations · Full text

Cryo-em Structures, Biomaterials Design, Hiapp Fibrils +3

O-GlcNAc forces an α-synuclein amyloid strain with notably diminished seeding and pathology

Aaron T. Balana, Anne‐Laure Mahul‐Mellier, Binh A. Nguyen et al. · Nature Chemical Biology · 2024 · 74 citations · Full text

Common fibrillar spines of amyloid-β and human islet amyloid polypeptide revealed by microelectron diffraction and structure-based inhibitors

Pascal Krotee, Sarah L. Griner, M.R. Sawaya et al. · Journal of Biological Chemistry · 2017 · 60 citations · Full text

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