BRAF and RAS oncogenes regulate Rho GTPase pathways to mediate migration and invasion properties in human colon cancer cells: a comparative study

Eleni Makrodouli, Eftychia Oikonomou, Michal Koc, +4

Molecular Cancer

p38 MAPK plays an essential role in apoptosis induced by photoactivation of a novel ethylene glycol porphyrin derivative

Jarmila Králová, M Dvořák, Michal Koc, +1

Oncogene

Signal TransductionEssential RoleBiochemistryPhotochemistryMedicine +11

Weight Loss Improves the Adipogenic Capacity of Human Preadipocytes and Modulates Their Secretory Profile

Lenka Rossmeislová, Lucia Mališová, Jana Kračmerová, +7

Diabetes

Novel Porphyrin Conjugates with a Potent Photodynamic Antitumor Effect: Differential Efficacy of Mono‐ and Bis‐β‐cyclodextrin Derivatives <i>In Vifro</i> and <i>In Vivo</i>

Jarmila Králová, Alla Synytsya, P Poučková, +2

Photochemistry and Photobiology

Exercise Training Reduces Inflammation of Adipose Tissue in the Elderly: Cross-Sectional and Randomized Interventional Trial

Terezie Čížková, Marek Štěpán, Klára Daďová, +10

The Journal of Clinical Endocrinology & Metabolism

Selective BRAFV600E Inhibitor PLX4720, Requires TRAIL Assistance to Overcome Oncogenic PIK3CA Resistance

Eftychia Oikonomou, Michal Koc, Vladimíra Šourková, +2

PLoS ONE

Inhibition of Lipolysis Ameliorates Diabetic Phenotype in a Mouse Model of Obstructive Sleep Apnea

Martin Weiszenstein, Larissa A. Shimoda, Michal Koc, +2

American Journal of Respiratory Cell and Molecular Biology

Adipogenesis, lipogenesis and lipolysis is stimulated by mild but not severe hypoxia in 3T3-L1 cells

Martin Weiszenstein, Martina Musutova, Andrea Plíhalová, +8

Biochemical and Biophysical Research Communications

Metabolic SyndromeMedicinePhysiologyHypoxia (Medicine)Metabolic Regulation +10

Cell death induced by taxanes in breast cancer cells: cytochrome C is released in resistant but not in sensitive cells.

Marie Ehrlichová, Michal Koc, Jaroslav Truksa, +3

PubMed

The plant alkaloid and anti-leukemia drug homoharringtonine sensitizes resistant human colorectal carcinoma cells to TRAIL-induced apoptosis via multiple mechanisms

Lenka Beranová, António Pombinho, Jarmila Stremenova Spegarova, +6

APOPTOSIS

Plant AlkaloidMedicineApoptosisHerb-drug InteractionCell Death +6