Gopal Parthasarathy

Restoring Methicillin-Resistant <i>Staphylococcus aureus</i> Susceptibility to β-Lactam Antibiotics

Christopher M. Tan, Alex G. Therien, Jun Lü et al. · Science Translational Medicine · 2012 · 244 citations

Mechanism of Action of the Cell-Division Inhibitor PC190723: Modulation of FtsZ Assembly Cooperativity

Nathaniel L. Elsen, Jun Lu, Gopal Parthasarathy et al. · Journal of the American Chemical Society · 2012 · 130 citations

Crystal Structure, Cooperative Assembly, Protein Assembly +20

Identification of an allosteric binding site for RORγt inhibition

Marcel Scheepstra, S. Leysen, Geert C. van Almen et al. · Nature Communications · 2015 · 100 citations · Full text

From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9

Whitney L. Petrilli, Gregory C. Adam, Roman S. Erdmann et al. · Cell chemical biology · 2019 · 80 citations · Full text

Biochemistry, Medicine, Natural Sciences +9

Identification and in Vivo Evaluation of Liver X Receptor β-Selective Agonists for the Potential Treatment of Alzheimer’s Disease

Shawn J. Stachel, Celina Zerbinatti, Michael T. Rudd et al. · Journal of Medicinal Chemistry · 2016 · 47 citations · Full text

Pharmacotherapy, Agonist Series, Alzheimer ’ +22