Guru Pavan Kumar Seerapu

Spiro heterocycles as potential inhibitors of SIRT1: Pd/C-mediated synthesis of novel N-indolylmethyl spiroindoline-3,2′-quinazolines

D. Rambabu, Guttikonda Raja, B. Yogi Sreenivas et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 52 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

AlCl3-mediated hydroarylation–heteroarylation in a single pot: a direct access to densely functionalized olefins of pharmacological interest

Ali Nakhi, Sivakumar Archana, Guru Pavan Kumar Seerapu et al. · Chemical Communications · 2013 · 47 citations

Natural Sciences, Chemistry, Medicinal Chemistry +10

A novel SIRT1 inhibitor, 4bb induces apoptosis in HCT116 human colon carcinoma cells partially by activating p53

Ananga Ghosh, Amrita Sengupta, Guru Pavan Kumar Seerapu et al. · Biochemical and Biophysical Research Communications · 2017 · 47 citations

Medicine, Cancer Biology, Oncology +16

Transition metal free hydrolysis/cyclization strategy in a single pot: synthesis of fused furo N-heterocycles of pharmacological interest

Ali Nakhi, Md. Shafiqur Rahman, Guru Pavan Kumar Seerapu et al. · Organic & Biomolecular Chemistry · 2013 · 30 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

Amberlite IR-120H catalyzed MCR: Design, synthesis and crystal structure analysis of 1,8-dioxodecahydroacridines as potential inhibitors of sirtuins

Ali Nakhi, Padaki Srinivas, Md. Shafiqur Rahman et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 29 citations

Pharmacy, Chemistry, Medicinal Chemistry +11