A CRISPR-based approach for targeted DNA demethylation

Xingxing Xu, Yonghui Tao, Xiaobo Gao, +7

Cell Discovery

Systems BiologyEngineeringOff-target EffectDna MethylationMolecular Biology +12

Ubiquitylation of Autophagy Receptor Optineurin by HACE1 Activates Selective Autophagy for Tumor Suppression

Zhengzhao Liu, Peng Chen, Hong Gao, +18

Cancer Cell

Cell AutophagyMitophagySignal TransductionSignaling PathwayReceptor Tyrosine Kinase +9

SARM1 promotes neuroinflammation and inhibits neural regeneration after spinal cord injury through NF-κB signaling

Huitao Liu, Jingjing Zhang, Xingxing Xu, +17

Theranostics

Astrocytic YAP protects the optic nerve and retina in an experimental autoimmune encephalomyelitis model through TGF-β signaling

Qian Wu, Xuemeng Miao, Jingjing Zhang, +20

Theranostics

Astrocytic YAP Promotes the Formation of Glia Scars and Neural Regeneration after Spinal Cord Injury

Changnan Xie, Xiya Shen, Xingxing Xu, +21

Journal of Neuroscience

YAP prevents premature senescence of astrocytes and cognitive decline of Alzheimer's disease through regulating CDK6 signaling

Xingxing Xu, Xiya Shen, Jiaojiao Wang, +11

Aging Cell

Identification of novel hub genes associated with liver metastasis of gastric cancer

Wenjun Chang, Liye Ma, Liping Lin, +13

International Journal of Cancer

Novel Hub GenesTumor BiologyMedicinePathologyCancer Genomics +12

Development and Validation of an IDH1-Associated Immune Prognostic Signature for Diffuse Lower-Grade Glioma

Xiangyang Deng, Dongdong Lin, Bo Chen, +10

Frontiers in Oncology

Activity-induced synaptic delivery of the GluN2A-containing NMDA receptor is dependent on endoplasmic reticulum chaperone Bip and involved in fear memory

Xiaomin Zhang, Xunyi Yan, Bin Zhang, +13

Cell Research

Activity-induced Synaptic DeliverySynaptic PlasticityPsychiatryNeurophysiologyMedicine +8

D-galactose induces senescence of glioblastoma cells through YAP-CDK6 pathway

Xingxing Xu, Xiya Shen, Wenjin Feng, +15

Aging

Chemoprevention StrategyApoptosisLamin B1Cell ProliferationGlioma +17