Jan-Jacob Schuringa

Constitutive Stat3, Tyr705, and Ser727 phosphorylation in acute myeloid leukemia cells caused by the autocrine secretion of interleukin-6

Jan-Jacob Schuringa, Albertus T.J. Wierenga, W. Kruijer et al. · Blood · 2000 · 184 citations

Ser727‐dependent transcriptional activation by association of p300 with STAT3 upon IL‐6 stimulation

Jan-Jacob Schuringa, Hein Schepers, Edo Vellenga et al. · FEBS Letters · 2001 · 121 citations

Molecular Regulation, Immunology, Immune Regulation +20

Interleukin-6-induced STAT3 transactivation and Ser727 phosphorylation involves Vav, Rac-1 and the kinase SEK-1/MKK-4 as signal transduction components

Jan-Jacob Schuringa, Luigi J.C. Jonk, Wim H.A. Dokter et al. · Biochemical Journal · 2000 · 99 citations · Full text

Immunology, Immune Regulation, Innate Immunity +21

Sequential Activation of Rac-1, SEK-1/MKK-4, and Protein Kinase Cδ Is Required for Interleukin-6-induced STAT3 Ser-727 Phosphorylation and Transactivation

Jan-Jacob Schuringa, Lodewijk V. Dekker, Edo Vellenga et al. · Journal of Biological Chemistry · 2001 · 82 citations · Full text

c-Jun AND c-Fos COOPERATE WITH STAT3 IN IL-6-INDUCED TRANSACTIVATION OF THE IL-6 RESPONSE ELEMENT (IRE)

Jan-Jacob Schuringa, Hilko Timmer, Daniël Luttickhuizen et al. · Cytokine · 2001 · 70 citations

Inflammation, Cytokine, Immune Cell Development +7