Phuc Leo H. Vo

Transposon-encoded CRISPR–Cas systems direct RNA-guided DNA integration

Sanne E. Klompe, Phuc Leo H. Vo, Tyler S. Halpin-Healy et al. · Nature · 2019 · 641 citations

Life Sciences, Genetics, Molecular Biology +10

CRISPR RNA-guided integrases for high-efficiency, multiplexed bacterial genome engineering

Phuc Leo H. Vo, Carlotta Ronda, Sanne E. Klompe et al. · Nature Biotechnology · 2020 · 344 citations · Full text

Life Sciences, Genetics, Microbiology +14

Targeted DNA integration in human cells without double-strand breaks using CRISPR-associated transposases

George D. Lampe, Rebeca T. King, Tyler S. Halpin-Healy et al. · Nature Biotechnology · 2023 · 138 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Programmable gene insertion in human cells with a laboratory-evolved CRISPR-associated transposase

Isaac P. Witte, George D. Lampe, Simon Eitzinger et al. · Science · 2025 · 78 citations · Full text

Life Sciences, Biotechnology, Genetics +14

Selective TnsC recruitment enhances the fidelity of RNA-guided transposition

Florian T. Hoffmann, Minjoo Kim, Leslie Y. Beh et al. · Nature · 2022 · 71 citations · Full text

Life Sciences, Genetics, Molecular Biology +3