Heather Domaschenz

A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity

Carola G. Vinuesa, Matthew Cook, Constanza Angelucci et al. · Nature · 2005 · 855 citations

Immunogenetics, Autoimmune Disease, T-regulatory Cell +8

Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production

Katrina L. Randall, Teresa Lambe, Andrew L. Johnson et al. · Nature Immunology · 2009 · 252 citations

Immunogenetics, Developmental Biology, Germinal Centers +3

CD83 increases MHC II and CD86 on dendritic cells by opposing IL-10–driven MARCH1-mediated ubiquitination and degradation

Lina E. Tze, Keisuke Horikawa, Heather Domaschenz et al. · The Journal of Experimental Medicine · 2011 · 219 citations · Full text

Adaptive Immune System, Innate Immune System, Immunology +25

Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection

Andrew L. Johnson, L. Aravind, Natalia Shulzhenko et al. · Nature Immunology · 2009 · 122 citations · Full text

Biology, Thymocyte Positive Selection, Genetics +9

Human lymphoma mutations reveal CARD11 as the switch between self-antigen–induced B cell death or proliferation and autoantibody production

Yogesh Jeelall, James Q. Wang, Hsei Di Law et al. · The Journal of Experimental Medicine · 2012 · 43 citations · Full text