BTK inhibition targets in vivo CLL proliferation through its effects on B-cell receptor signaling activity

Shuhua Cheng, Jiao Ma, Ailin Guo, +7

Leukemia

Vivo Cll ProliferationSignal TransductionSignaling PathwayCell RegulationReceptor Tyrosine Kinase +8

Functional characterization of BTKC481S mutation that confers ibrutinib resistance: exploration of alternative kinase inhibitors

Sijie Cheng, Ailin Guo, Ping Lu, +3

Leukemia

MedicineBtkc481s MutationReceptor Tyrosine KinaseConfers Ibrutinib ResistanceMolecular Biology +6

Glucose limitation activates AMPK coupled SENP1-Sirt3 signalling in mitochondria for T cell memory development

Jianli He, Xun Shangguan, Wei Zhou, +25

Nature Communications

SENP1-Sirt3 signaling promotes α-ketoglutarate production during M2 macrophage polarization

Wei Zhou, Gaolei Hu, Jianli He, +14

Cell Reports

InflammationSignal TransductionM2 PolarizationSignaling PathwayMacrophage Activation +12

Characterization of ibrutinib‐sensitive and ‐resistant mantle lymphoma cells

Jiao Ma, Pin Lu, Ailin Guo, +5

British Journal of Haematology

Rb⁺ cations enable the change of luminescence properties in perovskite (Rb_xCs_1−xPbBr₃) quantum dots

Hao Wu, Yong Yang, Dacheng Zhou, +7

Nanoscale

BTK Inhibition Targets in Vivo CLL Proliferation Through Its Effects On B-Cell Receptor Signaling Activity.

Y. Lynn Wang, Shuhua Cheng, Jiao Ma, +7

Blood

SIRT3 deacetylase activity confers chemoresistance in AML via regulation of mitochondrial oxidative phosphorylation

Jiao Ma, Bin Liu, Dan Yu, +4

British Journal of Haematology

Chemoprevention StrategyApoptosisCell DeathMitochondrial Oxidative PhosphorylationReactive Oxygen Species +16

NRF2 SUMOylation promotes de novo serine synthesis and maintains HCC tumorigenesis

Haoyan Guo, Jiaqian Xu, Quan Zheng, +10

Cancer Letters

Cerdulatinib, a novel dual SYK/JAK kinase inhibitor, has broad anti-tumor activity in both ABC and GCB types of diffuse large B cell lymphoma

Jiao Ma, Xing Wei, Greg Coffey, +8

Oncotarget

ImmunologyPathologyCell DeathGcb DlbclTumor Biology +18