Jeffrey J. DeStefano

Polymerization and RNase H activities of the reverse transcriptases from avian myeloblastosis, human immunodeficiency, and Moloney murine leukemia viruses are functionally uncoupled.

Jeffrey J. DeStefano, Rodolfo G. Buiser, Lisa M. Mallaber et al. · Journal of Biological Chemistry · 1991 · 150 citations · Full text

Viral Replication, Immunology, Molecular Biology +17

Requirements for strand transfer between internal regions of heteropolymer templates by human immunodeficiency virus reverse transcriptase

Jeffrey J. DeStefano, Lisa M. Mallaber, Philip J. Fay et al. · Journal of Virology · 1992 · 129 citations · Full text

Viral Replication, Strand Transfer Synthesis, Molecular Biology +17

Selection of 2′-deoxy-2′-fluoroarabinonucleotide (FANA) aptamers that bind HIV-1 reverse transcriptase with picomolar affinity

Irani Alves Ferreira‐Bravo, Christopher Cozens, Philipp Holliger et al. · Nucleic Acids Research · 2015 · 124 citations · Full text

Determinants of the RNase H cleavage specificity of human immunodeficiency virus reverse transcriptase

Jeffrey J. DeStefano, Lisa M. Mallaber, Philip J. Fay et al. · Nucleic Acids Research · 1993 · 81 citations · Full text

Viral Replication, Genetics, Immunology +16

The mechanism of human immunodeficiency virus reverse transcriptase-catalyzed strand transfer from internal regions of heteropolymeric RNA templates.

Jeffrey J. DeStefano, Robert A. Bambara, Philip J. Fay · Journal of Biological Chemistry · 1994 · 73 citations · Full text

Viral Replication, Natural Sequence Rna, Viral Polymerase Mechanism +17