Francisco R. Portell

Mitochondrial Gene Therapy Augments Mitochondrial Physiology in a Parkinson's Disease Cell Model

Paula M. Keeney, Caitlin Quigley, Lisa D. Dunham et al. · Human Gene Therapy · 2009 · 87 citations · Full text

Recombinant mitochondrial transcription factor A with N-terminal mitochondrial transduction domain increases respiration and mitochondrial gene expression

Shilpa Iyer, Ravindar R. Thomas, Francisco R. Portell et al. · Mitochondrion · 2009 · 55 citations · Full text

Reductive Stress, Mitochondrial Function, Genetics +5

Recombinant human mitochondrial transcription factor A stimulates mitochondrial biogenesis and ATP synthesis, improves motor function after MPTP, reduces oxidative stress and increases survival after endotoxin

Ravindar R. Thomas, Shaharyar M. Khan, Francisco R. Portell et al. · Mitochondrion · 2010 · 53 citations

Mitochondrial Biogenesis, Mitochondrial Function, Cell Signaling +8

RhTFAM treatment stimulates mitochondrial oxidative metabolism and improves memory in aged mice

Ravindar R. Thomas, Shaharyar M. Khan, Rafal Smigrodzki et al. · Aging · 2012 · 51 citations · Full text

Aging, Rhtfam Treatment, Mitochondrial Biology +22

Safety and efficacy of once-daily HU6 versus placebo in people with non-alcoholic fatty liver disease and high BMI: a randomised, double-blind, placebo-controlled, phase 2a trial

Mazen Noureddin, Shaharyar M. Khan, Francisco R. Portell et al. · ˜The œLancet. Gastroenterology & hepatology · 2023 · 35 citations

Obesity, Metabolic Syndrome, Hepatology +9