Riley D. Metcalfe

The structure of the extracellular domains of human interleukin 11α receptor reveals mechanisms of cytokine engagement

Riley D. Metcalfe, Kaheina Aizel, Courtney O. Zlatic et al. · Journal of Biological Chemistry · 2020 · 55 citations · Full text

Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy

Stanley C. Xie, Riley D. Metcalfe, Elyse Dunn et al. · Science · 2022 · 53 citations · Full text

The structure of the PA28–20S proteasome complex from Plasmodium falciparum and implications for proteostasis

Stanley C. Xie, Riley D. Metcalfe, Eric Hanssen et al. · Nature Microbiology · 2019 · 42 citations

Protein Function, Protein Assembly, Biochemistry +9

Design of proteasome inhibitors with oral efficacy in vivo against <i>Plasmodium falciparum</i> and selectivity over the human proteasome

Stanley C. Xie, Riley D. Metcalfe, Hirotake Mizutani et al. · Proceedings of the National Academy of Sciences · 2021 · 35 citations · Full text

Functional and structural analysis of cytokine-selective IL6ST defects that cause recessive hyper-IgE syndrome

Yin‐Huai Chen, Diane B. Zastrow, Riley D. Metcalfe et al. · Journal of Allergy and Clinical Immunology · 2021 · 33 citations

Inflammation, Cytokine-selective Il6st Defects, Immunogenetics +14