Motomu Nakatake

Intratumoral expression of IL-7 and IL-12 using an oncolytic virus increases systemic sensitivity to immune checkpoint blockade

Shinsuke Nakao, Yukinori Arai, Mamoru Tasaki et al. · Science Translational Medicine · 2020 · 188 citations

Life Sciences, Immunology, Oncology +17

lncRNA UCA1-Mediated Cdc42 Signaling Promotes Oncolytic Vaccinia Virus Cell-to-Cell Spread in Ovarian Cancer

Kosuke Horita, Hajime Kurosaki, Motomu Nakatake et al. · Molecular Therapy — Oncolytics · 2019 · 38 citations · Full text

Medicine, Cancer Biology, Oncology +17

Fusogenic oncolytic vaccinia virus enhances systemic antitumor immune response by modulating the tumor microenvironment

Motomu Nakatake, Nozomi Kuwano, Emi Kaitsurumaru et al. · Molecular Therapy · 2020 · 27 citations · Full text

Medicine, Immunology, Oncology +17

Partial Deletion of Glycoprotein B5R Enhances Vaccinia Virus Neutralization Escape while Preserving Oncolytic Function

Motomu Nakatake, Hajime Kurosaki, Nozomi Kuwano et al. · Molecular Therapy — Oncolytics · 2019 · 23 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Long noncoding RNA UCA1 enhances sensitivity to oncolytic vaccinia virus by sponging miR-18a/miR-182 and modulating the Cdc42/filopodia axis in colorectal cancer

Kosuke Horita, Hajime Kurosaki, Motomu Nakatake et al. · Biochemical and Biophysical Research Communications · 2019 · 22 citations · Full text

Life Sciences, Molecular Biology, Oncology +17