Mamoru Tasaki

Intratumoral expression of IL-7 and IL-12 using an oncolytic virus increases systemic sensitivity to immune checkpoint blockade

Shinsuke Nakao, Yukinori Arai, Mamoru Tasaki et al. · Science Translational Medicine · 2020 · 175 citations

IL-7 coupled with IL-12 increases intratumoral T cell clonality, leading to complete regression of non-immunogenic tumors

Mamoru Tasaki, M. Yamashita, Yukinori Arai et al. · Cancer Immunology Immunotherapy · 2021 · 25 citations · Full text

Discovery of KRAS(G12D) selective degrader ASP3082

Tomohiro Yoshinari, Takeyuki Nagashima, Hiroki Ishioka et al. · Communications Chemistry · 2025 · 18 citations · Full text

Abstract 5735: Novel KRAS G12D degrader ASP3082 demonstrates in vivo, dose-dependent KRAS degradation, KRAS pathway inhibition, and antitumor efficacy in multiple KRAS G12D-mutated cancer models

Takeyuki Nagashima, Tomohiro Yoshinari, Yoshihiro Nishizono et al. · Cancer Research · 2023 · 17 citations

Dose-dependent Kras Degradation, Asp3082 Monotherapy, Abstract 5735 +17

Leber's hereditary optic neuropathy with 14484 mutation in Central Java, Indonesia

Tomoki Nishioka, Mamoru Tasaki, Augustinus Soemantri et al. · Journal of Human Genetics · 2003 · 14 citations · Full text

Ophthalmology, Genetic Disorder, Genetics +10