Ariën S. Rustenburg

Hypoxia Induces Production of L-2-Hydroxyglutarate

Andrew M. Intlekofer, Raymond G. Dematteo, Sriram Venneti et al. · Cell Metabolism · 2015 · 497 citations · Full text

Redox Regulator, Medicine, Physiology +7

Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations

Andrew M. Intlekofer, Alan H. Shih, Bo Wang et al. · Nature · 2018 · 271 citations · Full text

Somatic Variant, Genetics, Dimer-interface Mutations +8

L-2-Hydroxyglutarate production arises from noncanonical enzyme function at acidic pH

Andrew M. Intlekofer, Bo Wang, Hui Liu et al. · Nature Chemical Biology · 2017 · 264 citations

Biotransformation, Cellular Enzymology, Biochemistry +7

Biomolecular Simulations under Realistic Macroscopic Salt Conditions

Gregory A. Ross, Ariën S. Rustenburg, Patrick Grinaway et al. · The Journal of Physical Chemistry B · 2018 · 108 citations

Binding Modes of Ligands Using Enhanced Sampling (BLUES): Rapid Decorrelation of Ligand Binding Modes via Nonequilibrium Candidate Monte Carlo

Samuel C. Gill, Nathan M. Lim, Patrick Grinaway et al. · The Journal of Physical Chemistry B · 2018 · 86 citations · Full text