Metformin inhibits lithocholic acid-induced interleukin 8 upregulation in colorectal cancer cells by suppressing ROS production and NF-kB activity

Thi Thinh Nguyen, Trong Thuan Ung, Shinan Li, +4

Scientific Reports

TLR2 Limits Development of Hepatocellular Carcinoma by Reducing IL18-Mediated Immunosuppression

Shinan Li, Rui Sun, Yongyan Chen, +2

Cancer Research

Nicotine stimulates IL-8 expression via ROS/NF-κB and ROS/MAPK/AP-1 axis in human gastric cancer cells

Sen Lian, Shinan Li, Jun Zhu, +2

Toxicology

Cancer ResearchGastrointestinal OncologyMedicineNicotineImmunology +8

Apigenin Suppresses the IL-1β-Induced Expression of the Urokinase-Type Plasminogen Activator Receptor by Inhibiting MAPK-Mediated AP-1 and NF-κB Signaling in Human Bladder Cancer T24 Cells

Yong Xia, Miaomiao Yuan, Shinan Li, +6

Journal of Agricultural and Food Chemistry

Chemoprevention StrategyUpar ExpressionImmunologyCancer BiologyTumor Biology +15

Cholic Acid Stimulates MMP-9 in Human Colon Cancer Cells via Activation of MAPK, AP-1, and NF-κB Activity

Shinan Li, Trong Thuan Ung, Thi Thinh Nguyen, +3

International Journal of Molecular Sciences

Chemoprevention StrategyImmunologyPathologyP38 MapkCholangiopathies +14

Sulforaphane Suppresses the Nicotine-Induced Expression of the Matrix Metalloproteinase-9 via Inhibiting ROS-Mediated AP-1 and NF-κB Signaling in Human Gastric Cancer Cells

Shinan Li, Pham Ngoc Khoi, Hong Yin, +4

International Journal of Molecular Sciences

Chemoprevention StrategyNicotine-induced ExpressionCancer BiologyTumor BiologyOxidative Stress +17

Lithocholic Acid Induces miR21, Promoting PTEN Inhibition via STAT3 and ERK-1/2 Signaling in Colorectal Cancer Cells

Thi Thinh Nguyen, Thuan-Trong Ung, Shinan Li, +4

International Journal of Molecular Sciences

Promoter ActivityMedicineColorectal CancerPathologyPten Inhibition +13

UHPLC-MS-Based Serum and Urine Metabolomics Reveals the Anti-Diabetic Mechanism of Ginsenoside Re in Type 2 Diabetic Rats

Heyu Wang, Yaran Teng, Shinan Li, +4

Molecules

Nicotine stimulates IL‐6 expression by activating the AP‐1 and STAT‐3 pathways in human endothelial EA.hy926 cells

Trong Thuan Ung, Thi Thinh Nguyen, Sen Lian, +4

Journal of Cellular Biochemistry

Piperine Attenuates Lithocholic Acid-Stimulated Interleukin-8 by Suppressing Src/EGFR and Reactive Oxygen Species in Human Colorectal Cancer Cells

Shinan Li, Thi Thinh Nguyen, Trong Thuan Ung, +4

Antioxidants

Chemoprevention StrategyLipid PeroxidationImmunologyPathologyCrc Cells +16