Babita Ganguly

Design, synthesis and evaluation of a novel double pro-drug: INX-08189. A new clinical candidate for hepatitis C virus

Christopher McGuigan, Karolina Madela, Mohamed Aljarah et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 99 citations

Pharmacy, Medicinal Chemistry, Pharmacology +9

INX-08189, a Phosphoramidate Prodrug of 6-<i>O</i>-Methyl-2′-<i>C</i>-Methyl Guanosine, Is a Potent Inhibitor of Hepatitis C Virus Replication with Excellent Pharmacokinetic and Pharmacodynamic Properties

John Vernachio, Blair Bleiman, K. Dawn Bryant et al. · Antimicrobial Agents and Chemotherapy · 2011 · 84 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Phosphoramidate ProTides of 2′-<i>C</i>-Methylguanosine as Highly Potent Inhibitors of Hepatitis C Virus. Study of Their in Vitro and in Vivo Properties

Christopher McGuigan, Arnaud Gilles, Karolina Madela et al. · Journal of Medicinal Chemistry · 2010 · 56 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

Mefloquine pharmacokinetics and mefloquine-artesunate effectiveness in Peruvian patients with uncomplicated Plasmodium falciparum malaria

Julie Gutman, Michael Green, Salomón Durand et al. · Malaria Journal · 2009 · 54 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +15

Phosphorodiamidates as a Promising New Phosphate Prodrug Motif for Antiviral Drug Discovery: Application to Anti-HCV Agents

Christopher McGuigan, Karolina Madela, Mohamed Aljarah et al. · Journal of Medicinal Chemistry · 2011 · 54 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16