Chul H. Yu

Discovery of a Potent Small Molecule IL-2 Inhibitor through Fragment Assembly

Andrew C. Braisted, Johan D. Oslob, Warren L. DeLano et al. · Journal of the American Chemical Society · 2003 · 245 citations

Knockout of a starch synthase gene OsSSIIIa/Flo5 causes white-core floury endosperm in rice (Oryza sativa L.)

Nayeon Ryoo, Chul H. Yu, Cheon‐Seok Park et al. · Plant Cell Reports · 2007 · 193 citations

Biology, White-core Floury Endosperm, Biosynthesis +9

Discovery of a potent and selective Aurora kinase inhibitor

Johan D. Oslob, M.J. Romanowski, Darin A. Allen et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 107 citations · Full text

Signaling Pathway, Receptor Tyrosine Kinase, Medicine +4

Discovery and Development of Potent LFA-1/ICAM-1 Antagonist SAR 1118 as an Ophthalmic Solution for Treating Dry Eye

Min Zhong, Thomas R. Gadek, Minna Bui et al. · ACS Medicinal Chemistry Letters · 2012 · 94 citations · Full text

Ocular Disease, Immunology, Immunologic Mechanism +17

Integrating Fragment Assembly and Biophysical Methods in the Chemical Advancement of Small-Molecule Antagonists of IL-2:  An Approach for Inhibiting Protein−Protein Interactions

Brian C. Raimundo, Johan D. Oslob, Andrew C. Braisted et al. · Journal of Medicinal Chemistry · 2004 · 83 citations · Full text

Drug Target, Molecular Biology, Chemical Biology +16