Phase I trial of retroviral-mediated transfer of the human MDR1 gene as marrow chemoprotection in patients undergoing high-dose chemotherapy and autologous stem-cell transplantation.

Charles Hesdorffer, Janet Ayello, Maureen Ward, +8

Journal of Clinical Oncology

Targeting CD20+ Aggressive B-cell Non–Hodgkin Lymphoma by Anti-CD20 CAR mRNA-Modified Expanded Natural Killer Cells <i>In Vitro</i> and in NSG Mice

Yaya Chu, Jessica Hochberg, Ashlin Yahr, +5

Cancer Immunology Research

Expbnk-treated MiceImmunologyImmune RegulationCd4 T Cell ResponsesImmunotherapeutics +15

Obinutuzumab (GA101) compared to rituximab significantly enhances cell death and antibody-dependent cytotoxicity and improves overall survival against CD20+ rituximab-sensitive/-resistant Burkitt lymphoma (BL) and precursor B-acute lymphoblastic leukaemia

Aradhana Awasthi, Janet Ayello, Carmella van de Ven, +7

British Journal of Haematology

Obinutuzumab Versus RituximabImmunologyCell DeathPathologyImmunotherapeutics +14

Romidepsin alone or in combination with anti-CD20 chimeric antigen receptor expanded natural killer cells targeting Burkitt lymphoma <i>in vitro</i> and in immunodeficient mice

Yaya Chu, Ashlin Yahr, Brian Z. Huang, +3

OncoImmunology

Safety, Pharmacokinetics, and Immunomodulatory Effects of Lenalidomide in Children and Adolescents With Relapsed/Refractory Solid Tumors or Myelodysplastic Syndrome: A Children's Oncology Group Phase I Consortium Report

Stacey L. Berg, Mitchell S. Cairo, Heidi V. Russell, +6

Journal of Clinical Oncology

An Age-Dependent Pharmacokinetic Study of Intravenous and Oral Mycophenolate Mofetil in Combination with Tacrolimus for GVHD Prophylaxis in Pediatric Allogeneic Stem Cell Transplantation Recipients

Monica Bhatia, Olga Militano, Zhezhen Jin, +11

Biology of Blood and Marrow Transplantation

Protein phosphatase 1 regulatory subunit 1A in ewing sarcoma tumorigenesis and metastasis

Wen Luo, Che Xu, Janet Ayello, +4

Oncogene

MedicinePathologyProtein PhosphorylationRegulatory Subunit 1ATumor Suppressor +5

Ex vivo expansion, maturation, and activation of umbilical cord blood–derived T lymphocytes with IL-2, IL-12, anti-CD3, and IL-7

Kathleen L Robinson, Janet Ayello, Rose Hughes, +4

Experimental Hematology

Ex Vivo ExpansionUmbilical CordLymphocyte DevelopmentImmune Cell DevelopmentImmunology +10

Characterization of Cord Blood Natural Killer and Lymphokine Activated Killer Lymphocytes Following Ex Vivo Cellular Engineering

Janet Ayello, Carmella van de Ven, Weiwei Fortino, +8

Biology of Blood and Marrow Transplantation

Characterization of natural killer and natural killer–like T cells derived from ex vivo expanded and activated cord blood mononuclear cells: Implications for adoptive cellular immunotherapy

Janet Ayello, Carmella van de Ven, Evan Cairo, +4

Experimental Hematology

Cell TherapyMedicineImmunologyImmunodominanceT Cell Immunity +11