Thomas R. Holmes

The curcumin analog HO-3867 selectively kills cancer cells by converting mutant p53 protein to transcriptionally active wildtype p53

Esha Madan, Taylor M. Parker, Matthias R. Bauer et al. · Journal of Biological Chemistry · 2018 · 46 citations · Full text

Chemoprevention Strategy, Cell Death, Cancer Biology +16

Accumulation of cytoplasmic CDC25A in cutaneous squamous cell carcinoma leads to a dependency on CDC25A for cancer cell survival and tumor growth

Jenan Al‐Matouq, Thomas R. Holmes, Brianna Hammiller et al. · Cancer Letters · 2017 · 39 citations

Oncology, Medicine, Tumor Growth +11

CDC25B and CDC25C overexpression in nonmelanoma skin cancer suppresses cell death

Jenan Al‐Matouq, Thomas R. Holmes, Laura A. Hansen · Molecular Carcinogenesis · 2019 · 36 citations

Phosphatase-Inert Glucosamine 6-Phosphate Mimics Serve as Actuators of the <i>glmS</i> Riboswitch

Xiang Fei, Thomas R. Holmes, Julianna Diddle et al. · ACS Chemical Biology · 2014 · 28 citations

Bioorganic Chemistry, Glycobiology, Molecular Biology +16

Targeting 14-3-3ε activates apoptotic signaling to prevent cutaneous squamous cell carcinoma

Thomas R. Holmes, Jenan Al Matouq, Matti Holmes et al. · Carcinogenesis · 2020 · 18 citations · Full text