Hiroshi Ishiguro

Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: Metalloproteinase inhibitors as a new therapy

Masanori Asakura, Masafumi Kitakaze, Seiji Takashima et al. · Nature Medicine · 2002 · 718 citations

Adam12 Processing, Cardiac Muscle, Cardiomyopathy +9

Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription

Takayoshi Shimohata, Toshihiro Nakajima, Mitsunori Yamada et al. · Nature Genetics · 2000 · 397 citations

Molecular Physiology, Signal Transduction, Molecular Regulation +9

A general method for introducing a series of mutations into cloned DNA using the polymerase chain reaction

Wataru Ito, Hiroshi Ishiguro, Yoshikazu Kurosawa · Gene · 1991 · 248 citations

Polymerase Chain Reaction, Dna Sequencing, Reverse Genetics +12

The Signal Transducer and Activator of Transcription 1α and Interferon Regulatory Factor 1 Are Not Essential for the Induction of Indoleamine 2,3-Dioxygenase by Lipopolysaccharide: Involvement of p38 Mitogen-Activated Protein Kinase and Nuclear Factor-κB Pathways, and Synergistic Effect of Several Proinflammatory Cytokines

Hidetsugu Fujigaki, Kuniaki Saito, Suwako Fujigaki et al. · The Journal of Biochemistry · 2006 · 217 citations

Immunology, Immune Regulation, Immunologic Mechanism +20

Accumulation of intracellular HCO3‐ by Na(+)‐HCO3‐ cotransport in interlobular ducts from guinea‐pig pancreas.

Hiroshi Ishiguro, Martin C. Steward, A R Lindsay et al. · The Journal of Physiology · 1996 · 174 citations · Full text