Exosomes play a role in multiple myeloma bone disease and tumor development by targeting osteoclasts and osteoblasts

Sylvia Faict, Joséphine Muller, Kim De Veirman, +9

Blood Cancer Journal

Xenogeneic Graft-Versus-Host Disease in Humanized NSG and NSG-HLA-A2/HHD Mice

Grégory Ehx, Joan Somja, Hans-Jörg Warnatz, +11

Frontiers in Immunology

Granulocytic myeloid-derived suppressor cells promote angiogenesis in the context of multiple myeloma

Marilène Binsfeld, Joséphine Muller, Virginie Lamour, +8

Oncotarget

Hematological MalignancyMdsc SubsetsGranulocyteMalignant Blood DisorderImmunology +11

The anti‐mitotic agents PTC‐028 and PTC596 display potent activity in pre‐clinical models of multiple myeloma but challenge the role of <i>BMI‐1</i> as an essential tumour gene

Arnold Bolomsky, Joséphine Muller, Kathrin Stangelberger, +12

British Journal of Haematology

Azacytidine mitigates experimental sclerodermic chronic graft-versus-host disease

Gilles Fransolet, Grégory Ehx, Joan Somja, +11

Journal of Hematology & Oncology

SRC kinase inhibition with saracatinib limits the development of osteolytic bone disease in multiple myeloma

Roy Heusschen, Joséphine Muller, Marilène Binsfeld, +12

Oncotarget

Maternal embryonic leucine zipper kinase is a novel target for proliferation-associated high-risk myeloma

Arnold Bolomsky, Roy Heusschen, Karin Schlangen, +6

Haematologica

Maternal embryonic leucine zipper kinase inhibitor OTSSP167 has preclinical activity in multiple myeloma bone disease

Joséphine Muller, Arnold Bolomsky, Sophie Dubois, +13

Haematologica

Loss of Stromal Galectin-1 Enhances Multiple Myeloma Development: Emphasis on a Role in Osteoclasts

Joséphine Muller, Elodie Duray, Margaux Lejeune, +11

Cancers

Altered chondrocyte differentiation, matrix mineralization and MEK-Erk1/2 signaling in an INPPL1 catalytic knock-out mouse model of opsismodysplasia

Charles-Andrew Vande Catsyne, Sufyan Sayyed, Patricia Molina-Ortíz, +8

Advances in Biological Regulation