Regulatory Mechanisms for Adipose Tissue M1 and M2 Macrophages in Diet-Induced Obese Mice

Shiho Fujisaka, Isao Usui, Agussalim Bukhari, +9

Diabetes

Treatment with SRT1720, a SIRT1 activator, ameliorates fatty liver with reduced expression of lipogenic enzymes in MSG mice

Yu Yamazaki, Isao Usui, Yukiko Kanatani, +14

American Journal of Physiology-Endocrinology and Metabolism

Sirt1 ActivatorSrt1720 TreatmentFatty Liver DiseaseCaloric RestrictionObesity +16

Telmisartan Improves Insulin Resistance and Modulates Adipose Tissue Macrophage Polarization in High-Fat-Fed Mice

Shiho Fujisaka, Isao Usui, Yukiko Kanatani, +13

Endocrinology

Telmisartan TreatmentMetabolic DisorderImmunologyAdipose Tissue MacrophagesInsulin Signaling +21

Interleukin-1α Inhibits Insulin Signaling with Phosphorylating Insulin Receptor Substrate-1 on Serine Residues in 3T3-L1 Adipocytes

Jianying He, Isao Usui, Ken Ishizuka, +7

Molecular Endocrinology

Chronic Tumor Necrosis Factor-α Treatment Causes Insulin Resistance via Insulin Receptor Substrate-1 Serine Phosphorylation and Suppressor of Cytokine Signaling-3 Induction in 3T3-L1 Adipocytes

Ken Ishizuka, Isao Usui, Yukiko Kanatani, +11

Endocrinology

Serine PhosphorylationImmune RegulationImmunologyPathologyTnfalpha Stimulation +20

Effects of Pioglitazone on Suppressor of Cytokine Signaling 3 Expression

Yukiko Kanatani, Isao Usui, Ken Ishizuka, +7

Diabetes

Socs3 InductionImmunologyCell DeathInsulin SignalingInflammation +18

Long-term Interleukin-1α Treatment Inhibits Insulin Signaling via IL-6 Production and SOCS3 Expression in 3T3-L1 Adipocytes

Takao Uno, Jiaping He, Isao Usui, +11

Hormone and Metabolic Research

Sirt1 activator induces proangiogenic genes in preadipocytes to rescue insulin resistance in diet-induced obese mice

Allah Nawaz, Arshad Mehmood, Yukiko Kanatani, +9

Scientific Reports

Deletion of platelet-derived growth factor receptor-β improves diabetic nephropathy in Ca2+/calmodulin-dependent protein kinase IIα (Thr286Asp) transgenic mice

Hikari Suzuki, Isao Usui, I. Kato, +13

Diabetologia

Signal TransductionMolecular PhysiologyMedicineDiabetesImmunology +9

Angiotensin II enhances the increase in monocyte chemoattractant protein-1 production induced by tumor necrosis factor-α from 3T3-L1 preadipocytes

Sachie Asamizu, Masaharu Urakaze, Chikaaki Kobashi, +14

Journal of Endocrinology