Amit Nathubhai

Structure-Based Dissection of the Natural Product Cyclopentapeptide Chitinase Inhibitor Argifin

Ole A. Andersen, Amit Nathubhai, Mark J. Dixon et al. · Chemistry & Biology · 2008 · 66 citations · Full text

Chitinase Inhibitors, Linear Peptides, Structure-based Dissection +12

Radiosensitization with an inhibitor of poly(ADP-ribose) glycohydrolase: A comparison with the PARP1/2/3 inhibitor olaparib

Polly Gravells, James R. Neale, Emma K. Grant et al. · DNA repair · 2017 · 59 citations · Full text

Highly Potent and Isoform Selective Dual Site Binding Tankyrase/Wnt Signaling Inhibitors That Increase Cellular Glucose Uptake and Have Antiproliferative Activity

Amit Nathubhai, T. Haikarainen, Jarkko Koivunen et al. · Journal of Medicinal Chemistry · 2016 · 55 citations · Full text

Structure-based design, synthesis and evaluation in vitro of arylnaphthyridinones, arylpyridopyrimidinones and their tetrahydro derivatives as inhibitors of the tankyrases

Katerina P. Kumpan, Amit Nathubhai, Chenlu Zhang et al. · Bioorganic & Medicinal Chemistry · 2015 · 42 citations · Full text

Medicinal Chemistry, Biochemistry, Natural Sciences +8

Design and Discovery of 2-Arylquinazolin-4-ones as Potent and Selective Inhibitors of Tankyrases

Amit Nathubhai, Pauline J. Wood, Matthew D. Lloyd et al. · ACS Medicinal Chemistry Letters · 2013 · 41 citations · Full text

Combinatorial Chemistry, Selective Tnks Inhibitors, Organic Chemistry +18