Steven Schaffert

A clinically meaningful metric of immune age derived from high-dimensional longitudinal monitoring

Ayelet Alpert, Yishai Pickman, Michael D. Leipold et al. · Nature Medicine · 2019 · 502 citations · Full text

Retrospective Cohort Study, Immune Age, Autoimmune Disease +14

Single-Cell Chromatin Modification Profiling Reveals Increased Epigenetic Variations with Aging

Peggie Cheung, Francesco Vallania, Hayley Warsinske et al. · Cell · 2018 · 322 citations · Full text

Chromatin, Aging, Chromatin Remodeling +10

Antigen Recognition Determinants of γδ T Cell Receptors

Sunny Shin, Ramy El–Diwany, Steven Schaffert et al. · Science · 2005 · 177 citations

T22 Recognition, T-regulatory Cell, Immune Regulation +16

Leveraging heterogeneity across multiple datasets increases cell-mixture deconvolution accuracy and reduces biological and technical biases

Francesco Vallania, Andrew Tam, Shane Lofgren et al. · Nature Communications · 2018 · 174 citations · Full text

Precise Gene Deletion and Replacement Using the CRISPR/Cas9 System in Human Cells

Qiupeng Zheng, Xiaohong Cai, Meng How Tan et al. · BioTechniques · 2014 · 153 citations · Full text

Gene Deletion, Off-target Effect, Functional Genomics +14