Yoshihiko Norimine

Discovery of 2-(2-Oxo-1-phenyl-5-pyridin-2-yl-1,2-dihydropyridin-3-yl)benzonitrile (Perampanel): A Novel, Noncompetitive α-Amino-3-hydroxy-5-methyl-4-isoxazolepropanoic Acid (AMPA) Receptor Antagonist

Shigeki Hibi, Koshi Ueno, Satoshi Nagato et al. · Journal of Medicinal Chemistry · 2012 · 177 citations

Synaptic Transmission, Pyridone Ring, Neurotransmitter +21

Chemoenzymatic Synthesis of Antiviral Carbocyclic Nucleosides:  Asymmetric Hydrolysis of <i>meso</i>-3,5-Bis(acetoxymethyl)cyclopentenes Using <i>Rhizopus </i><i>delemar</i> Lipase

Masakazu Tanaka, Yoshihiko Norimine, Toshiaki Fujita et al. · The Journal of Organic Chemistry · 1996 · 43 citations

Chemoenzymatic Synthesis, Antiviral Carbocyclic Nucleosides, Bioorganic Chemistry +14

Enantioselective Synthesis of (−)-Curcumanolide A Using Enzymatic Transesterification of <i>meso</i>-Spirodiol

Toshiaki Fujita, Masakazu Tanaka, Yoshihiko Norimine et al. · The Journal of Organic Chemistry · 1997 · 35 citations

Biosynthesis, Meso-spirodiol 12, Engineering +13

Practical Synthesis of Chiral Emopamil Left Hand as a Bioactive Motif

Teiji Kimura, Noboru Yamamoto, Yuichi Suzuki et al. · The Journal of Organic Chemistry · 2002 · 31 citations

Methyl Aluminum Bis, Practical Synthesis, Enantioselective Synthesis +15

Asymmetric synthesis of the δ-lactone moiety in mevinic acid derivatives using an enzymatic procedure

Hidetaka Kaku, Masakazu Tanaka, Yoshihiko Norimine et al. · Tetrahedron Asymmetry · 1997 · 15 citations

Derivative (Chemistry), Derivatives, Engineering +10