Nachiappan Dhatchana Moorthy

DNA Damage-induced Expression of p53 Suppresses Mitotic Checkpoint Kinase hMps1

Mandar Bhonde, Marie‐Luise Hanski, Jan Budczies et al. · Journal of Biological Chemistry · 2006 · 45 citations · Full text

Life Sciences, Cancer Biology, Oncology +17

Synthesis and Biological Evaluation of Calothrixins B and their Deoxygenated Analogues

Bose Muthu Ramalingam, Nachiappan Dhatchana Moorthy, Somenath Roy Chowdhury et al. · Journal of Medicinal Chemistry · 2018 · 41 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +15

The broad-range cyclin-dependent kinase inhibitor UCN-01 induces apoptosis in colon carcinoma cells through transcriptional suppression of the Bcl-xL protein

Mandar Bhonde, Marie‐Luise Hanski, Roberta Magrini et al. · Oncogene · 2004 · 27 citations

Life Sciences, Cell Biology, Oncology +16

Synthesis of 2-substituted 17β-hydroxy/17-methylene estratrienes and their in vitro cytotoxicity in human cancer cell cultures

Ganapathy Panchapakesan, V. Dhayalan, Nachiappan Dhatchana Moorthy et al. · Steroids · 2011 · 19 citations

Medicine, Chemistry, Pharmacology +5

Novel isothiacalothrixin B analogues exhibit cytotoxic activity on human colon cancer cells in vitro by inducing irreversible DNA damage

Nachiappan Dhatchana Moorthy, Bose Muthu Ramalingam, Saleem Iqbal et al. · PLoS ONE · 2018 · 15 citations · Full text

Medicine, Oncology, Pharmacology +13