David Ciccone

Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5

Konstantinos J. Mavrakis, E. Robert McDonald, Michael R. Schlabach et al. · Science · 2016 · 580 citations

Medicine, Cancer Biology, Oncology +16

Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX

Craig H. Bassing, Katrin F. Chua, JoAnn Sekiguchi et al. · Proceedings of the National Academy of Sciences · 2002 · 528 citations

Life Sciences, Genetics, Molecular Biology +17

KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints

David Ciccone, Hui Su, Sarah Hevi et al. · Nature · 2009 · 512 citations

Life Sciences, Genetics, Molecular Biology +14

RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination

Adam G. W. Matthews, Alex Kuo, Santiago Ramón‐Maiques et al. · Nature · 2007 · 463 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response

Xiaohua Wu, Velvizhi Ranganathan, David Weisman et al. · Nature · 2000 · 445 citations

Life Sciences, Biochemistry, Molecular Biology +16