Harini P Tirumala

Acute MeCP2 loss in adult mice reveals transcriptional and chromatin changes that precede neurological dysfunction and inform pathogenesis

Sameer S. Bajikar, Jian Zhou, Ryan O’Hara et al. · Neuron · 2024 · 26 citations · Full text

Life Sciences, Genetics, Neuroscience +17

Identification and characterization of conserved noncoding <i>cis</i>-regulatory elements that impact <i>Mecp2</i> expression and neurological functions

Yingyao Shao, Sameer S. Bajikar, Harini P Tirumala et al. · Genes & Development · 2021 · 17 citations · Full text

Life Sciences, Genetics, Neuroscience +15

A novel pathogenic mutation of MeCP2 impairs chromatin association independent of protein levels

Jian Zhou, Claudia Cattoglio, Yingyao Shao et al. · Genes & Development · 2023 · 16 citations · Full text

Life Sciences, Genetics, Neuroscience +17

Modeling antisense oligonucleotide therapy in <i>MECP2</i> duplication syndrome human iPSC-derived neurons reveals gene expression programs responsive to MeCP2 levels

Sameer S. Bajikar, Yehezkel Sztainberg, Alexander J. Trostle et al. · Human Molecular Genetics · 2024 · 10 citations · Full text

Life Sciences, Genetics, Neuroscience +17