Kuojun Zhang

Novel Biphenyl Pyridines as Potent Small-Molecule Inhibitors Targeting the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction

Tianyu Wang, Shi Cai, Mingming Wang et al. · Journal of Medicinal Chemistry · 2021 · 81 citations · Full text

Structure-Based Design of a Selective Class I Histone Deacetylase (HDAC) Near-Infrared (NIR) Probe for Epigenetic Regulation Detection in Triple-Negative Breast Cancer (TNBC)

Kuojun Zhang, Zhiyi Liu, Yiwu Yao et al. · Journal of Medicinal Chemistry · 2021 · 45 citations · Full text

Discovery of Small Molecules Simultaneously Targeting NAD(P)H:Quinone Oxidoreductase 1 and Nicotinamide Phosphoribosyltransferase: Treatment of Drug-Resistant Non-small-Cell Lung Cancer

Kuojun Zhang, Kaizhen Wang, Xiangyu Zhang et al. · Journal of Medicinal Chemistry · 2022 · 28 citations · Full text

Aldo-keto Reductase, Compound 10D, Nad+ Metabolism +20

Dual Nicotinamide Phosphoribosyltransferase (NAMPT) and Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors for the Treatment of Drug-Resistant Nonsmall-Cell Lung Cancer

Kaizhen Wang, Ke Ye, Xiangyu Zhang et al. · Journal of Medicinal Chemistry · 2023 · 25 citations · Full text

Design, Synthesis, and Evaluation of PD-1/PD-L1 Antagonists Bearing a Benzamide Scaffold

Lu Lu, Zhihao Qi, Tianyu Wang et al. · ACS Medicinal Chemistry Letters · 2022 · 22 citations · Full text