Jens E. Ruhe

Fibroblast growth factor receptor 4 regulates proliferation, anti-apoptosis and alpha-fetoprotein secretion during hepatocellular carcinoma progression and represents a potential target for therapeutic intervention

Han Kiat Ho, Sharon Pok, Sylvia Streit et al. · Journal of Hepatology · 2008 · 190 citations

Hepatology, Alpha-fetoprotein Secretion, Hepatocellular Carcinoma +9

Genetic Alterations in the Tyrosine Kinase Transcriptome of Human Cancer Cell Lines

Jens E. Ruhe, Sylvia Streit, Stefan Hart et al. · Cancer Research · 2007 · 85 citations

The FGFR4 Y367C mutant is a dominant oncogene in MDA-MB453 breast cancer cells

Andreas Roidl, Priscilla Foo, Willy Wong et al. · Oncogene · 2009 · 63 citations · Full text

Fgfr4 Y367c Mutant, Medicine, Cancer Cell Biology +7

Clinical Translation and Validation of a Predictive Biomarker for Patritumab, an Anti-human Epidermal Growth Factor Receptor 3 (HER3) Monoclonal Antibody, in Patients With Advanced Non-small Cell Lung Cancer

Jeanne Mendell, Daniel J. Freeman, Wenqin Feng et al. · EBioMedicine · 2015 · 48 citations · Full text

EGFR signaling leads to downregulation of PTP-LAR via TACE-mediated proteolytic processing

Jens E. Ruhe, S. Streit, Sarah Hart et al. · Cellular Signalling · 2006 · 43 citations

Signal Transduction, Signaling Pathway, Medicine +8