Geert Jan Sterk

Histamine H2-receptor agonists. Synthesis, in vitro pharmacology, and qualitative structure-activity relationships of substituted 4- and 5-(2-aminoethyl)thiazoles

J. Ch. Eriks, H. van der Goot, Geert Jan Sterk et al. · Journal of Medicinal Chemistry · 1992 · 98 citations · Full text

Pharmacological Validation of Trypanosoma brucei Phosphodiesterases as Novel Drug Targets

Harry P. de Koning, Matthew K. Gould, Geert Jan Sterk et al. · The Journal of Infectious Diseases · 2012 · 93 citations · Full text

Medicinal Chemistry, Drug Target, Trypanosomal Pdes +14

Probing biomembrane interfacial potential and pH profiles with a new type of float-like fluorophores positioned at varying distance from the membrane surface

Ruud Kraayenhof, Geert Jan Sterk, Harro W. Wong Fong Sang · Biochemistry · 1993 · 77 citations

Novel Selective PDE4 Inhibitors. 1. Synthesis, Structure−Activity Relationships, and Molecular Modeling of 4-(3,4-Dimethoxyphenyl)-2<i>H</i>-phthalazin-1-ones and Analogues

Margaretha Van der Mey, Armin Hatzelmann, Ivonne J. Van der Laan et al. · Journal of Medicinal Chemistry · 2001 · 74 citations · Full text

Synthesis and Structure−Activity Relationships of<i>cis</i>-Tetrahydrophthalazinone/Pyridazinone Hybrids:  A Novel Series of Potent Dual PDE3/PDE4 Inhibitory Agents

Margaretha Van der Mey, Kirsten M. Bommelé, Hildegard Boss et al. · Journal of Medicinal Chemistry · 2003 · 65 citations · Full text

Organic Chemistry, Pharmacotherapy, New Series +16